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Bluetongue Virus As A Cause Of Hydranencephaly In Cattle
Hydranencephaly was produced in a foetus and a calf by intra-uterine infection with an attenuated Type 10 bluetongue virus. Laparotomy was performed on the respective dams and the foetust:s, respectively 126 days and 138 days old, were inoculated intramuscularly through the uterine wall with 1 ml of a virus suspension containing 5 x 10³ tissue culture infective doses. The younger foetus was aborted on Day 262, while the other one was born alive on Day 273. Both foetuses showed marked hydranencephaly.