EduCoast study resource
Free to study
A Biomimetic Approach To The Synthesis Of A Mycolic Acid Motif
A new method for the stereoselective synthesis of the (R,R)-b-hydroxy-a-alkyl fatty acid fragment of mycolic acids, via an asymmetric anti-aldol reaction is reported. The ‘mycolic acid motif’ fragment was prepared in three steps and >98% ee.